2016 Schedule

The course begins at 8:30am on Monday and will conclude Thursday at 3:00pm. The course is held in Keller Hall room 3-180/3-176
(course topics subject to change)

In-Depth Sessions

In-Depth Sessions

  • Cell Culture Data Analysis and Visualization
    This hands-on session will use templates for automated cell culture data processing, calculation, and plotting. We will also demonstrate visualization and analysis of large sets of historical data.
  • Primer on DOE (JMP) 
    DOE is now an integral part of QbD. This session will cover the basic concept of DOE, and provide an overview of software JMP.
  • Pipeline and Software for Chinese Hamster Genomic Data Analysis 
    This session will illustrate the basics of using Galaxy to map RNA seq data to Chinese hamster genome, the comparison of cell line genome to a reference genome and answer questions on genome and transcriptome analysis. In the optional follow up session, you will have the opportunity to browse data and explore on your own.
  • Analysis of Large Process Data 
    Archived process data and genomic data contains troves of hidden information. This session will review the conceptual framework of pattern recognition to find hidden trends.
  • Cell Metabolism and Lactate Consumption 
    Metabolic characteristics in early stage culture seems to have an imprint in the production reaction; and the switching to lactate consumption in late stage is correlated to high productivity. This session will discuss fundamentals on such behavior and means to manipulate metabolism.

Monday, June 13 

Monday, June 13 

Keller Hall 3-180

Topic Lecturer
Registration  
Overview of Cell Culture Technology Hu
Cell Biology for Process Engineering Hu
Break  
Cell Biology for Process Engineering (Continued) Hu
Stoichiometry and Kinetics of Cell Growth and Product Formation Hu
Recess  
Stoichiometry and Kinetics of Cell Growth and Product Formation (continued) Hu
Cell Phisiology for Process Engineering Hu
Break  
Cell Physiology for Process Engineering (continued) Hu
Break  
Cell Culture Data Analysis
-Data Organization and Processing
-Historical Data Visualization
-Metabolic Flux Analysis
Hu
Reception TBD

 

Tuesday, June 14

Tuesday, June 14

Keller Hall 3-180

Topic Lecturer
Cell Culture Bioreactor Hu
Medium Design for Cell Culture Processing Hu
Break  
Medium Design for Cell Culture Processing (continued) Hu
Break  
Methods and Strategies in Cell Line Development Seth
Recess  
Methods and Strategies in Cell Line Development (continued) Seth
Break  
Oxygen Transfer Hu
Cell Culture Data Analysis Hu
Break  
Case Studies  
Discussion Hu
Optional Breakout Sessions  
1. Flux Analysis Keller 3-180
2. Cell Metabolism and Lactate Consumption Amundson 240

 

Wednesday, June 15

Wednesday, June 15

Keller 3-180

Topic Lecturer
Process Analytical Technology Zhou
Fed-Batch Culture and Dynamic Nutrient Feeding Zhou
Break  
Scale-up and Scale-down of Cell Culture Processes Hu
Recess  
Stem Cell Technology and Cell Therapy Azarin
Quality by Design in Cell Culture Processing Abu-Absi
Break  
Cell Culture Genomics and Informatics Hu
Break  
Cell Retention and Continuous Process Zhou
Wine and Cheese, Poster Display at Weisman Art Museum  
Dinner at Weisman Art Museum, Dolly Fiterman Riverview Gallery  

 

Thursday, June 16 - Workshop

Thursday, June 16 - Workshop

30 years in Workshops on Cell Culture Engineering
Keller 3-180

Topic Lecturer
Workshop Introduction Hu
Introduction to Microbiome Adams
Clinical Manufacturing of Cell Therapy McKenna
Break  
Glycosylation Control Hossler
Challenges and Opportunities in Future Biomanufacturing  

-Continuous Processing

Zhou

-Material Control for Single Use Supplies and Reagents

Seth

-QbD: Toward Product Real Time Release

Abu-Absi

-Cell Line Development and Systems Biotechnology

Hu
Recess  
Forum  
Break  
Summary and Conclusion  

 

Contact Us

Molly Jokimaki
University of Minnesota
421 Washington Avenue SE
280 Amundson Hall
Minneapolis, MN 55455 USA
+1 (612) 626-7630
acre@umn.edu